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CardiovascularNeuromodulation Lab

Research program

Connecting neural control, cardiovascular physiology, and brain health

We study neural cardiovascular control, brain blood flow, and neuromodulation through five connected research areas.

Scientific scope

These are research areas, not evidence of clinical effectiveness or individual suitability.

Research area 1

Neural Control of Blood Pressure

We study how neural reflexes and sympathetic activity work together to regulate blood pressure and circulation in humans.

  • Muscle sympathetic nerve activity
  • Arterial and cardiopulmonary baroreflexes
  • Chemoreflexes
  • Integrated autonomic regulation

Research area 2

Cardiovascular Instability in Neurological Disease

We investigate blood-pressure instability and autonomic cardiovascular problems associated with neurological conditions.

  • Orthostatic hypotension
  • Supine hypertension
  • Autonomic dysreflexia
  • Parkinson's disease
  • Spinal cord injury
  • Stroke
  • Multiple sclerosis

Research area 3

Neuromodulation and Precision Interventions

We examine device-based, physiological, pharmacological, and closed-loop approaches intended to restore or support cardiovascular control.

  • Device-based approaches
  • Physiological interventions
  • Pharmacological approaches
  • Closed-loop concepts
  • Individualized physiological measurement

Research area 4

Cerebrovascular Function and Brain Health

We study how brain blood flow adapts to blood-pressure and metabolic changes, including pressure autoregulation during squat-to-stand and carbon-dioxide reactivity during RespirAct-controlled ramped hypercapnia.

  • Dynamic cerebral autoregulation
  • Cerebrovascular reactivity
  • Neurovascular coupling
  • Blood-pressure instability
  • Brain health

Research area 5

Human Physiology Methods and Open Research Tools

We advance human experimentation, physiological signal analysis, reproducible methods, training, and accessible research tools.

  • Integrative human physiology
  • Physiological signal analysis
  • Reproducible methods
  • Research training
  • Accessible analysis tools

How we study human physiology

Explore what we do